Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids.
Distinct transcriptional states are maintained through organization PWR REC Sofa with ADJ Headrest of chromatin, resulting from the sum of numerous repressive and active histone modifications, into tightly packaged heterochromatin versus more accessible euchromatin.Polycomb repressive complex 2 (PRC2) is the main mammalian complex responsible for h